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Title: Potent antibacterial activity of oligo-3-aminopyridine against Staphylococcus aureus and Enterococcus faecalis
Authors: Akgul, Cahit
Kaya, Ismet
Keywords: Antibacterial activity;S. aureus;E. faecalis;oligo-3-aminopyridine
Issue Date: Apr-2004
Publisher: CSIR
Abstract: Oligo-3-aminopyridine (OAP) was tested for its antibacterial activity against two gram positive (Staphylococcus aureus and Enterococcus faecalis) and two gram negative (Escherchia coli and Pseudomonas aeruginosa) bacterial strains. Antibacterial efficacy was measured by disk diffusion assay. Inhibition zones demonstrated that 50 μg OAP showed strong antibacterial activity against the gram-positive strains; the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were found to be 25 μg/ml and 50 μg/ml, respectively. The results indicate that OAP is a potent antibacterial agent against S. aureus and E. faecalis.
Page(s): 120-122
ISSN: 0301-1208
Appears in Collections:IJBB Vol.41(2&3) [April-June 2004]

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