NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.42 [2005] >
IJBB Vol.42(2) [April 2005] >

Title: Age-related changes in the elemental constituents and molecular behaviour of bone
Authors: Rai, D V
Darbari, R
Aggarwal, L M
Keywords: Bone
Energy dispersive X-ray
Elemental analysis
IR spectra
Age-related changes
Issue Date: Apr-2005
Publisher: CSIR
IPC CodeG01N 33/50
Abstract: Age-related changes in bone composition within the age groups of 30, 60, 120 and 180 days in rats have been studied using thermogravimetery, elemental analysis and energy dispersive X-ray (ED X-ray). The structural changes in rats the bone samples were monitored by IR spectroscopy. The main constituents of hydroxyapatite, namely Ca, P and their oxides were analyzed. Organic changes, such as C and N contents in the matrix were found to have a predominant role in the initial development of the bone. An incremental increase in the mineral content of bone with advancing age was also observed. Elemental composition (C and N contents) was observed to be independent of age at the initial stages. The amount of Ca and its oxide content was found to increase, and the P and its oxides showed a decreasing trend, with the advancing age. IR spectra revealed that the mineral phase comprised both amorphous and crystalline hydroxyapatite, even at maturity; the amorphous content being higher at the earlier stages (14.09%, at 30 days), but was gradually replaced by crystalline component with advancing age (63.09% at 180 days). The present data may be useful in explaining the ageing phenomenon and helpful in understanding the bone growth and remodeling.
Page(s): 127-130
ISSN: 0301-1208
Source:IJBB Vol.42(2) [April 2005]

Files in This Item:

File Description SizeFormat
IJBB 42(2) 127-130.pdf142.62 kBAdobe PDFView/Open
 Current Page Visits: 108 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 170163 since 01-Sep-2015  Last updated on 30-Jun-2016Webmaster: