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Title: Synthesis and anti-mycobacterial activity of 1H-1,2,3-triazolylisonicotinohydrazides
Authors: Dayakar, Ch
Suman, P
Rajkumar, K
Yogeeswari, P
Sriram, D
Raju, B China
Keywords: 2-Chloronicotinaldehydes;1H-1,2,3-triazolylisonicotinohydrazides;synthesis;anti-mycobacterial activity;cytotoxicity
Issue Date: Jul-2016
Publisher: NISCAIR-CSIR, India
Abstract: 1H-1,2,3-Triazolylisonicotinohydrazides (7a-d and 13a-f) have been prepared by the condensation of 1H-1,2,3-triazole-4-carbaldehydes (5a-d and 12a-f) with isonicotinylhydrazide (INH, 6) in good yields. All the synthesized compounds (7a-d and 13a-f) have been screened for their anti-mycobacterial activity. Compounds 7a, 7b and 13b display good anti-mycobacterial activity and these derivatives have been chosen for their cytotoxicity
Page(s): 882-887
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(07) [July 2016]

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