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Title: Advanced synthetic and pharmacological aspects of 1,3-oxazoles and benzoxazoles
Authors: Ghani, Ambreen
Hussain, Erum A
Sadiq, Zubi
Naz, Narjis
Keywords: Benzoxazole;bisoxazole;oxazole;synthesis;bioactivity
Issue Date: Jul-2016
Publisher: NISCAIR-CSIR, India
Abstract: Broad bio-spectrum of 1,3-oxazole and benzoxazole has created an attractive platform for synthetic chemists to introduce structural modification in its nucleus by straight forward access to new approaches. Owing to its fascinating features and interesting pharmacological activities, many researchers have proved that oxazole is an active agent in treating different diseases. Based on this fact, this article outlines intramolecular and two component intermolecular cyclization to oxazoles and benzoxazoles. The theme is well documented in this review article covering the era from 2007 till present. Moreover, bioactivity and mechanistic insights are provided with different synthetic approaches, encompassing various pathways.
Page(s): 833-853
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(07) [July 2016]

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