Please use this identifier to cite or link to this item:
Title: Pharmacognostical and larvicidal evaluation of Artocarpus lakoocha Roxb. from Western Ghats
Authors: Prashanthi, P
Rajamma, A J
Sateesha, S B
Chandan, K
Tiwari, S N
Ghosh, S K
Keywords: Artocarpus lakoocha Roxb.;Aedes aegypti;Anopheles stephensi;Culex quinquefasciatus;HPTLC;Mosquito larvicidal activity;Pharmacognostical evaluation
Issue Date: Jun-2016
Publisher: NISCAIR-CSIR, India
IPC Code: Int. cl. (2015.01)− A61K 36/00, A61K 127/00, A61K 131/00, A61P 29/00, A61P 33/06
Abstract: Mosquitoes are the most important single group of insects acting as vector for many tropical and subtropical diseases. Using insecticides of plant origin to interrupt the life cycle, vector borne diseases can be controlled. Artocarpus lakoocha Roxb. popularly known as Monkey Jack or Lakuch is ethnobotanically used to treat fever, purge, skin ailments and also as an appetizer. The present study investigated the pharmacognostical and larvicidal activity of leaves and fruits of A. lakoocha against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus larvae. As a step towards standardization of crude drug, the powder microscopy, physico-chemical analysis, TLC studies and HPTLC profiles of active pet ether extract were established. The larvicidal potential of successive solvent extracts were screened and expressed as LC50 values. The pet ether extract of leaves and fruits were significant with LC50 241.36, 624.88, 1162.86 and 1180.95, 1286.69, 1398.69 µg/mL on the three species, respectively compared to other extracts. The results indicate that the triterpenoids and phytosterols present in the pet ether extract exerted a dose dependent larvicidal activity and the malarial vector, An. stephensi was more susceptible to the pet ether extract.
Page(s): 141-149
ISSN: 0976-0512 (Online); 0976-0504 (Print)
Appears in Collections: IJNPR Vol.7(2) [June 2016]

Files in This Item:
File Description SizeFormat 
IJNPR 7(2) 141-149.pdf489.76 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.