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Title: A convenient route to benzimidazole fused chiral heterocyclic bases
Authors: Wagh, Swapnil J
Tawde, Trupti S
Sapre, Jai V
Khose, Vaibhav N
Karnik, Anil V
Keywords: Benzimidazole;Organocatalyst;Chiral bases;Fused heterocycles;Multiple hetero-atoms
Issue Date: Jun-2016
Publisher: NISCAIR-CSIR, India
Abstract: An efficient synthetic protocol has been developed to obtain new chiral heterocyclic bases pyrrolo-benzimidazoles (DHP-Bz) and thiazolo-benzimidazoles (DHT-Bz). Notable characteristic of both series of the fused heterocycles is the presence of a chiral center. Chiral HPLC separations of the fused heterocycles have been achieved. These molecules possess structural features well-suited to function as chiral organocatalysts after resolution, apart from potential biological activities.
Page(s): 707-712
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(06) [June 2016]

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