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IJC-B Vol.48B(02) [February 2009] >


Title: ZrCl₄ promoted efficient one-pot synthesis of ⍺-amino nitriles
Authors: Raghu, M
Reddy, Ch Sanjeeva
Keywords: ZrCl₄
One-pot method
⍺-amino nitriles
Issue Date: Feb-2009
Publisher: CSIR
Abstract: A convenient and efficient one-pot method for the synthesis of a variety of α-amino nitriles from aldehydes, amines and trimethylsilyl cyanide in the presence of a catalytic amount of ZrCl₄ at room temperature is described. A simple work-up procedure, inexpensive and non-toxic catalyst, shorter reaction times along with excellent product yields are the significant features of this practical method.
Page(s): 295-300
ISSN: 0376-4699
Source:IJC-B Vol.48B(02) [February 2009]

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