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Title: Analysis of phytochemical, antimicrobial, and antioxidant properties of Sarcandra glabra (Thunb.) Nakai in relation to its ethnomedicinal relevance in Cordillera, Philippines
Authors: Chan, Maida Fatima E
Geronimo, Arnold Joseph O
Aspiras, Allan Paolo F
Busaing, Ezra Jair W
Dato, Ronald Joseph B
Calumpit, Donna May A
Cariaga, Liliamar B
Elizaga, Jhodel Ann C
Lafuente, Angelica T
Keywords: Ethnomedicine;Sarcandra glabra (Thunb.) Nakai;Phytochemical screening;Antimicrobial susceptibility testing;Antioxidant testing;Cordillera;Kalanguya tribe
Issue Date: Jul-2016
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8:C09K 15/00, C07, C07D 311/30, C07C, A61K 36/00
Abstract: Sarcandra glabra (Thunb.) Nakai, one of the ethnomedicinal plants used by the Cordillerans, is believed to treat various ailments based from the existing ethnoknowledge of Kalanguya tribe. However, scientific recognition of its claimed clinical consequences is limited. Hence, this research aims to identify its bioactive compounds as well as its antimicrobial and free radical scavenging activity which may be used to evaluate its potency. Standard tests for evaluating different bioactive compounds were employed for the identification of present phytochemicals. Results showed the presence of carbohydrates, phytosterols mainly diterpenes and triterpenes, phenolic compounds, flavonoids and proteins. In the assessment of its antimicrobial potential against Escherichia coli and Staphylococcus aureus, Kirby-Bauer Disc Diffusion method was employed; and the extract demonstrated negative inhibition against these bacteria. 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was executed for the detection of its antioxidant property, and the result showed that S. glabra has a free radical scavenging activity indicated by a decrease in the absorption of DPPH as the concentration of the extract increases. Findings indirectly suggest the therapeutic assertions potentiality of the ethnomedicinal plant. Therefore, clinical therapeutic trials are recommended to confirm therapeutic claims.
Page(s): 411-416
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.15(3) [July 2016]

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