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Title: A convenient one-pot synthesis of series of 3-(2,6-diphenyl-4- pyridyl)hydroquinolin-2-one under microwave irradiation and their antimicrobial activities
Authors: Ladani, Niraj K
Patel, Manish P
Patel, Ranjan G
Keywords: Microwave irradiation;2-chloro-3-formyl quinoline;Acetophenone;N-phenacylpyridinium chloride;Krohnke’s reaction condition
Issue Date: Feb-2009
Publisher: CSIR
Abstract: A series of 3-(2,6-diphenyl-4-pyridyl)hydroquinolin-2-one 4a-x compounds are synthesized in high yields by one pot cyclocondensation reactions under Krohnke’s reaction conditions using 2-chloro-3-formyl quinoline 1a-d, various acetophenone 2a-f, N-phenacylpyridinium chloride 3 in the mixture of ammonium acetate and acetic acid by microwave irradiation. All the compounds have been characterized by elemental analysis, FT- IR, ¹H and ¹³C NMR, and mass spectral analysis. These compounds have been screened for their antimicrobial activities.
Page(s): 261-266
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(02) [February 2009]

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