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Title: Novel hybrid natural products derived from solanesol as wound healing agents
Authors: Srivastava, Shefali
Raj, Kanwal
Khare, Pratibha
Bhaduri, Amiya P
Chander, Ramesh
Raghubir, Ram
Mahendra, K
Rao, C V Narsimha
Prabhu, S R
Keywords: Solanesol;Angiogenesis;Antioxidant;Wound healing activity
Issue Date: Feb-2009
Publisher: CSIR
Abstract: A series of compounds 2a-g, 3a,b, 4a-n have been synthesized from solanesol 1, an acyclic terpenoid alcohol, extracted from tobacco waste. These compounds have been evaluated for antioxidant, angiogenesis and wound healing activity. Compounds 3b and 4h exhibit better wound healing activity in comparison to 3,3-dimethylacryl shikonin. These results indicate that Solanesol derivatives can be further developed as wound healing agents.
Page(s): 237-247
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.48B(02) [February 2009]

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