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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.48B [2009] >
IJC-B Vol.48B(02) [February 2009] >
| Title: | Facile, high regio- and chemoselective conversion of epoxides to β-chlorohydrins using chlorodiphenylphosphine under solvent-free conditions |
| Authors: | Aghapour, Ghasem
Afzali, Asieh
Salek, Fahimeh |
| Keywords: | Epoxides
β-chlorohydrins
Chemoselectivity
Chlorodiphenylphosphine
Solvent-free |
| Issue Date: | Feb-2009 |
| Publisher: | CSIR |
| Abstract: | A new method is described for the mild and high regioselective conversion of epoxides to β-chlorohydrins in high yields even in the presence of alcohols, carboxylic acids, oximes, amides, thiols and tetrahydropyranyl ethers using chlorodiphenylphosphine (ClPPh₂) under solvent-free and neutral conditions at room temperature and in short reaction times. In addition, some other functional groups such as carbon-carbon double bonds, ester groups and also phenyl ring that are present in the epoxide molecules remain intact in this method. |
| Page(s): | 231-236 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.48B(02) [February 2009]
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