|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.43 [2006] >
IJBB Vol.43(6) [December 2006] >
| Title: | A new fragmentation rearrangement of the N-terminal protected |
| Authors: | Zhu, Zhen-Tai
Li, Yan-Mei
Guo, Yan-Ting
Sun, Ming
Zhao, Yu-Fen |
| Keywords: | Terminal-protected amino acids
ESI-MS/MS
Electronic migration
Rearrangement |
| Issue Date: | 2006 |
| Publisher: | CSIR |
| Abstract: | A novel fragmentation rearrangement reaction with a carboxyl oxygen negative charge migration was observed in the N-terminal protected amino acids including Fmoc-protected phosphoserine, phosphothroenine, and phosphotyrosine and their analogues using the electrospray ionization tandem mass spectrometry (ESI-MS/MS). The possible mechanism of a five-membered ring transition state was proposed and supported by the further experiments. It was found that the tendency of the rearrangement was determined by the blocking status of its C-terminal and the reaction was proved to be independent of the N-terminal and side-chain protecting groups of the amino acids. |
| Page(s): | 372-376 |
| ISSN: | 0301-1208 |
| Source: | IJBB Vol.43(6) [December 2006]
|
|
