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http://nopr.niscair.res.in/handle/123456789/3416
Title: | A new fragmentation rearrangement of the N-terminal protected |
Authors: | Zhu, Zhen-Tai Li, Yan-Mei Guo, Yan-Ting Sun, Ming Zhao, Yu-Fen |
Keywords: | Terminal-protected amino acids;ESI-MS/MS;Electronic migration;Rearrangement |
Issue Date: | 2006 |
Publisher: | CSIR |
Abstract: | A novel fragmentation rearrangement reaction with a carboxyl oxygen negative charge migration was observed in the N-terminal protected amino acids including Fmoc-protected phosphoserine, phosphothroenine, and phosphotyrosine and their analogues using the electrospray ionization tandem mass spectrometry (ESI-MS/MS). The possible mechanism of a five-membered ring transition state was proposed and supported by the further experiments. It was found that the tendency of the rearrangement was determined by the blocking status of its C-terminal and the reaction was proved to be independent of the N-terminal and side-chain protecting groups of the amino acids. |
Page(s): | 372-376 |
URI: | http://hdl.handle.net/123456789/3416 |
ISSN: | 0301-1208 |
Appears in Collections: | IJBB Vol.43(6) [December 2006] |
Files in This Item:
File | Description | Size | Format | |
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IJBB 43(6) 372-376.pdf | 255.7 kB | Adobe PDF | View/Open |
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