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Title: Synthesis and biological evaluation of some new pyrazoline derivatives as anti-inflammatory agents
Authors: Amir, Mohd
Ali, Sazid
Somakala, K
Keywords: Pyrazoline;Anti-inflammatory;Analgesic;Ulcerogenicity
Issue Date: Apr-2016
Publisher: NISCAIR-CSIR, India
Abstract: A series of pyrazolyl urea 3a-l and pyrazolyl sulphonamide 4a-l derivatives have been synthesized by the reaction of respective pyrazoline derivatives 2a-l with phenylisocyanate and p-acetamidobenzenesulphonylchloride respectively. All the synthesized compounds are characterized by IR, 1H NMR, mass spectral data, and elemental analysis. The compounds have been screened for their anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation potential.
Page(s): 478-485
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(04) [April 2016]

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