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Title: Iron-catalyzed cyclization of aminothiols: An easy access to benzothiazoles and evaluation of their antimicrobial and anti-biofilm activities
Authors: Vinayak, Botla
Reddy, Marri Anil
Chiranjeevi, Barreddi
Chandrashekharam, Malapaka
Poornachandra, Y
Kumar, Ganesh C
Keywords: Cyclization;Iron(III) chloride;Anticancer;Benzothiazoles;Antimicrobial activity;Staphylococcus aureus
Issue Date: Apr-2016
Publisher: NISCAIR-CSIR, India
Abstract: Iron-catalyzed cyclization of aminothiol with various aromatic and heteroaromatic aldehydes produces a variety of benzothiazoles in moderate to excellent yield. Compound 3o with one carbazole functional moiety bridged between two benzothiazole scaffolds is found promising and contributes to significant antimicrobial, MBC and anti-biofilm activities.
Page(s): 461-470
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(04) [April 2016]

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