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IJBB Vol.43(5) [October 2006] >


Title: Identification of α-2u globulin in the rat preputial gland by MALDI-TOF analysis
Authors: Ponmanickam, P
Archunan, G
Keywords: Pheromones
Preputial gland
Binding protein
Lipocalin
Rat
MALDI-TOF
Issue Date: 2006
Publisher: CSIR
Abstract: The low molecular mass proteins found in the pheromonal sources such as urine, saliva, glandular secretion etc have been reported as ligand carriers for the processes of chemo-communication in mammals. The preputial gland plays an important role in the production of olfactory signals for pheromonal communication. Thus, in the present study, α-2u globulin having molecular mass of 18 kDa has been identified in the preputial gland of Norway rat (Rattus norvegicus) by in-gel trypsin digestion and analyzing the resulting peptides by MALDI-TOF. Since preputial gland is one of the major pheromonal sources in rat, the results suggest that α-2u globulin might act as a carrier for hydrophobic odorants of preputial gland.
Page(s): 319-322
ISSN: 0301-1208
Source:IJBB Vol.43(5) [October 2006]

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