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dc.contributor.authorSadana, Tarun-
dc.contributor.authorSingh, Ran Vir-
dc.contributor.authorSingh, Shoor Vir-
dc.contributor.authorSaxena, Vishesh Kumar-
dc.contributor.authorSharma, Deepak-
dc.contributor.authorSingh, Pravin Kumar-
dc.contributor.authorKumar, Naveen-
dc.contributor.authorGupta, Saurabh-
dc.contributor.authorChaubey, Kundan Kumar-
dc.contributor.authorJayaraman, Sujata-
dc.contributor.authorTiwari, Ruchi-
dc.contributor.authorDhama, Kuldeep-
dc.contributor.authorBhatia, Ashok Kumar-
dc.contributor.authorSohal, Jagdip Singh-
dc.identifier.issn0975-0967 (Online); 0972-5849 (Print)-
dc.description.abstractJohne’s disease (JD) or paratuberculosis infection, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is one of the major production diseases of domestic animals. There is lack of preventive and chemotherapeutic measures to control this infection. Hence, in recent years emphasis has been given to identify host genetic factors associated with resistance to infection. In the present study, we analyzed SNPs in four candidate genes (SLC11A1, TLRs, NOD2/CARD and IFNγ) in case and control population of native breeds of cattle. Of the four genes only SNP in TLR2 gene showed significant association with resistance to paratuberculosis infection. The results of the present study are promising and it is predicted that such studies will serve as guidelines in future breeding programmes. en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJBT Vol.14(4) [October 2015]en_US
dc.subjectHost susceptibilityen_US
dc.subjectGenetic resistanceen_US
dc.subjectIndian cattleen_US
dc.subjectJohne’s diseaseen_US
dc.titleSingle nucleotide polymorphism of SLC11A1, CARD15, IFNG and TLR2 genes and their association with Mycobacterium avium subspecies paratuberculosis infection in native Indian cattle populationen_US
Appears in Collections:IJBT Vol.14(4) [October 2015]

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