Please use this identifier to cite or link to this item:
|Title:||Study on the antiproliferative activity of four Schiff bases derived from natural biomass dehydroabietylamine|
|Keywords:||Dehydroabietylamine;Schiff base;Antiproliferative activitiy;Structure-activity relationship|
|Abstract:||Four Schiff bases (1-4) have been obtained by the reaction of dehydroabietylamine and 5-fluoro-2-hydroxybenzaldehyde, 5-chloro-2-hydroxybenzaldehyde, 5-bromo-2-hydroxybenzaldehyde and 2-hydroxy-5-nitrobenzaldehyde, respectively. They have been evaluated for their antiproliferative activities over A549, NCI-H460 and SW620. Among them, 4 exhibits the highest antiproliferative activity. IC50 values are only 8.27, 2.98 and 7.14 μM for NCI-H460, SW620 and A549 cell lines, respectively.|
|Appears in Collections:||IJC-B Vol.55B(02) [February 2016]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.