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http://nopr.niscair.res.in/handle/123456789/33789| Title: | Study on the antiproliferative activity of four Schiff bases derived from natural biomass dehydroabietylamine |
| Authors: | Luo, Hui Sui, Yan Lin, Wen-Hua Wu, Hong-Qin |
| Keywords: | Dehydroabietylamine;Schiff base;Antiproliferative activitiy;Structure-activity relationship |
| Issue Date: | Feb-2016 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Four Schiff bases (1-4) have been obtained by the reaction of dehydroabietylamine and 5-fluoro-2-hydroxybenzaldehyde, 5-chloro-2-hydroxybenzaldehyde, 5-bromo-2-hydroxybenzaldehyde and 2-hydroxy-5-nitrobenzaldehyde, respectively. They have been evaluated for their antiproliferative activities over A549, NCI-H460 and SW620. Among them, 4 exhibits the highest antiproliferative activity. IC50 values are only 8.27, 2.98 and 7.14 μM for NCI-H460, SW620 and A549 cell lines, respectively. |
| Page(s): | 248-251 |
| URI: | http://hdl.handle.net/123456789/33789 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.55B(02) [February 2016] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 55B(2) 248-251.pdf | 118.15 kB | Adobe PDF | View/Open |
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