Please use this identifier to cite or link to this item:
|Title:||Synthesis of 1,2,3-triazole glycosides as anticancer agents|
|Keywords:||O-Methyl allose;Triazole glycosides;Click reaction;ZrCl4;Anticancer activity|
|Abstract:||A series of novel 1,2,3-Triazole glycosides have been prepared by the addition reaction of O-methyl allose aldehyde with Grignard reagent. Subsequent treatment with TMSN3 gives the corresponding azide, which on reaction with alkynes gives 1,2,3-triazole glycosides. Characterization of all the compounds has been carried out by IR, 1H NMR, mass spectroscopy and elemental analysis. Anticancer activity of the compounds has also been evaluated.|
|Appears in Collections:||IJC-B Vol.55B(02) [February 2016]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.