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Title: DABCO prompted tandem and multicomponent synthetic protocol of pyrano[2,3-a]acridines
Authors: Satheeshkumar, Rajendran
Kaminsky, Werner
Prasad, Karnam Jayarampillai Rajendra
Keywords: DABCO;Multi-component reaction;Tandem process;Pyrano[2,3-a]acridines
Issue Date: Feb-2016
Publisher: NISCAIR-CSIR, India
Abstract: An elegant synthesis of pyrano[2,3-a]acridines is presented, where 7-chloro-9-phenyl-3,4-dihydroacridin-1(2H)-one reacts with aryl aldehydes and malononitrile in a three-component system using 1,4-diazabicyclo[2.2.2]octane (DABCO) as catalyst in ethanol, giving excellent yields above those reached in a conventional step-wise approach. The structures of the synthesized compounds have been deduced by spectroscopic techniques, including X-ray diffraction.
Page(s): 220-230
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(02) [February 2016]

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