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Title: A new embelin from the mangrove Aegiceras corniculatum
Authors: Thota, Satya Prakasa Rao
Sarma, Nittala S
Murthy, Y L N
Keywords: Aegiceras corniculatum;Quinonoids;Antimalarial activity
Issue Date: Jan-2016
Publisher: NISCAIR-CSIR, India
Abstract: One new compound (2) and five known compounds (1, 3-6) have been isolated from the mangrove plant Aegiceras corniculatum collected from the Godavari mangrove forest, India. The structure of the new compound has been established by 1H and 13C NMR spectroscopy and mass spectral data as 2,5-didehydroxy-6-methylembelin (2). The known compounds have been characterized as 4-hydroxy-2-methoxybenzamide (1), embelin (3), 5-O-ethylembelin (4), 5-O-methylembelin (5) and 4-methoxyresorcinol (6). Compounds 2-5 exhibit moderate antimalarial activity. Embelin (3) shows activity against chloroquine-resistant strains better than against chloroquine-sensitive strains of Plasmodium falciparum.
Page(s): 123-127
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.55B(01) [January 2016]

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