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|Title:||A brief review of Cherylline synthesis|
|Authors:||Manolov, Stanimir P|
Atanasova, Stoyanka N
Ivanov, Iliyan I
|Abstract:||1,2,3,4-Tetrahydroisoquinolines are an important class of synthetic and natural compounds, which display a broad range of medicinal activities. The 1,2,3,4-tetrahydroisoquinoline system has attracted attention not only because of its biological activities, but also due to its presence as a basic framework in many naturally occurring products and drugs. Their skeletons are unique among the Amaryllidaceae alkaloids and they have long been alluring targets for synthetic chemists as witnessed by a number of articles dealing with biogenesis, isolation, characterization and synthesis. The alkaloid cherylline is an optically active naturally occurring, 4-phenyl-1,2,3,4-tetrahydroisoquinoline alkaloid, isolated from Crinum powelli, Amaryllidaceae plant. There are many ways for cherylline synthesis. In this short review is described the different methods for synthesis of the alkaloid cherylline.|
|Appears in Collections:||IJC-B Vol.54B(11) [November 2015]|
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