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Title: ZrOCl2.8H2O catalyzed solvent-free Friedlander synthesis of 1,8-naphthyridines
Authors: Mogilaiah, K
Rao, A Nageswara
Rao, P Koteswara
Keywords: Friedlander synthesis;2-aminonicotinaldehyde;Carbonyl compounds containing α-methylene group;ZrOCl2.8H2O;Solvent-free
Issue Date: Oct-2015
Publisher: NISCAIR-CSIR, India
Abstract: ZrOCl2.8H2O catalyzed Friedlander condensation of 2-amin-onicotinaldehyde 1 with carbonyl compounds containing α-methylene group 2 has been achieved in solvent-free grinding conditions to give 1,8-naphthyridines 3. The yields are very good and purity is excellent. The method is preparatively convenient and useful.
Page(s): 1280-1282
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.54B(10) [October 2015]

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