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dc.contributor.authorMulik, M B-
dc.contributor.authorLaddha, K S-
dc.identifier.issn0976-0512 (Online); 0976-0504 (Print)-
dc.description.abstractThe fruits of Piper cubeba L.f. have significance in traditional medicine (Ayurveda) and reports say that its activity is due to major lignan (-)-cubebin, which is a bioactive dibenzylbutyrolactone lignan and possess analgesic, anti-histaminic, antimicrobial and cytotoxic activities. Column chromatography is mostly used for the isolation of lignans from plant sources which is laborous and time consuming process. Therefore, the purpose of this research work is to develop simple and convenient method for isolation of (-)-cubebin from fruits of P cubeba L.f. The isolated compound was characterised by thin-layer chromatography (TLC), UV/visible spectroscopy (UV), infrared spectroscopy (IR), mass spectroscopy (MS) and nuclear magnetic resonance spectral analysis (NMR). Further high performance liquid chromatography (HPLC) was used to quantify (-)-cubebin in chloroform extract of the fruits. en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.relation.ispartofseriesInt. cl. (2014.01)−A61K 36/00en_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJNPR Vol.6(3) [September 2015]en_US
dc.subjectPiper cubeba L.fen_US
dc.titleIsolation, characterization and quantification of bioactive dibenzylbutyrolactone lignan (-)-cubebin from fruits of Piper cubeba L.f.en_US
Appears in Collections: IJNPR Vol.6(3) [September 2015]

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