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Title: Quality assessment and evaluation of in-vitro antioxidant potential of Phyllanthus emblica L.
Authors: Singh, Mhaveer
Khan, Mohammad Ahmed
Khan, Masood Shan
Ansari, SH
Ahmad, Sayeed
Keywords: Phyllanthus emblica L.;Physicochemical;TLC fingerprint;Antioxidant;Quality control
Issue Date: Apr-2015
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8: A61K 36/00, C09K 15/00, C12, G07C 3/14, A61B5/117, G06K 9/00
Abstract: Phyllanthus emblica L. syn. Emblica officinalis Gaertn. commonly known as amla is a well known drug in India having nutritional value with various health related benefits and employed in various herbal formulations due to the presence of high levels of vitamin C along with valuable phenolic constituents and amino acids. In the present study, quality assessment of amla fruit was carried out by studying macro and microscopic characters along with physicochemical tests for the identification of drug. Chemoprofiling was achieved with thin layer chromatography by optimizing the mobile phase for different extracts. Total phenolic contents and in-vitro antioxidant efficacy was also determined as the drug is well known for protective role in human body as antioxidant. The contaminant evaluation was carried out by analyzing the samples for the determination of heavy metals, pesticides and aflatoxins. The results of quality control and anatomical studies found useful for its identification with significant antioxidant efficacy. The drug was found free of contaminant when analyzed for pesticides and aflatoxins whereas heavy metals were found in safe limits. The work embodied in the present research can be utilized for the quality control and for the identification of the drug samples.
Page(s): 265-272
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.14(2) [April 2015]

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