Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/31671
Title: Ecofriendly synthesis of some benzothiazoles containing acridine moiety and their antimicrobial acitivity
Authors: Kawle, P R
Deohate, P P
Berad, B N
Keywords: Green chemistry;Benzothiazole;Antimicrobial screening
Issue Date: Jun-2015
Publisher: NISCAIR-CSIR, India
Abstract: Syntheses of benzothiazoles containing acridine moiety have been attempted by employing microwave irradiation method. (Acridin-9-yl-amino)-acetic acid N-(benzothiazol-2-yl)-hydrazides have been achieved by intramolecular oxidative cyclisation of (acridin-9-yl-amino)-acetic acid N-(N’-aryl-thioamido)-hydrazides using bromine in acetic acid. The required hydrazides have been synthesized by the interaction of (acridin-9-yl-amino)-acetic acid hydrazides with N-aryl isothiocyanates under microwave condition at 800 W. The structural elucidations of synthesised compounds have been performed by IR, 1H NMR and mass spectroscopic data and elemental analysis. The developed route is found to be satisfactory with improved yields, easy work-up and no environmental pollution. All the compounds have been found to possess potent antimicrobial response.
Page(s): 833-836
URI: http://hdl.handle.net/123456789/31671
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.54B(06) [June 2015]

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