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Title: | Identification of pharmacophores for anti-inflammatory and analgesic activity on aryl-(imidazol-1-yl) acetates |
Authors: | Sharma, R Rao, P S Shantanu Chaturvedi, S C |
Keywords: | 3D-QSAR;Pharmacophore;Anti-inflammatory activity;Analgesic activity;Apex-3D |
Issue Date: | Jun-2006 |
Publisher: | NISCAIR-CSIR, India |
IPC Code: | Int.Cl.8 C07D |
Abstract: | Rofecoxib being a selective cyclooygenase-2 inhibitor has been banned as a non-steroidal anti-inflammatory drug. This has opened new opportunities in the field of research and development of non steroidal anti-inflammatory drugs. In this search, pharmacophores for anti-inflammatory and analgesic activity based on aryl-(imidazol-1-yl) acetates have been identified. |
Page(s): | 1443-1452 |
URI: | http://hdl.handle.net/123456789/30708 |
ISSN: | 0042-6075 |
Appears in Collections: | IJC-B Vol.45B(06) [June 2006] |
Files in This Item:
File | Description | Size | Format | |
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IJCB 45B(6) 1443-1452.pdf | 1.57 MB | Adobe PDF | View/Open |
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