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http://nopr.niscair.res.in/handle/123456789/30708| Title: | Identification of pharmacophores for anti-inflammatory and analgesic activity on aryl-(imidazol-1-yl) acetates |
| Authors: | Sharma, R Rao, P S Shantanu Chaturvedi, S C |
| Keywords: | 3D-QSAR;Pharmacophore;Anti-inflammatory activity;Analgesic activity;Apex-3D |
| Issue Date: | Jun-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int.Cl.8 C07D |
| Abstract: | Rofecoxib being a selective cyclooygenase-2 inhibitor has been banned as a non-steroidal anti-inflammatory drug. This has opened new opportunities in the field of research and development of non steroidal anti-inflammatory drugs. In this search, pharmacophores for anti-inflammatory and analgesic activity based on aryl-(imidazol-1-yl) acetates have been identified. |
| Page(s): | 1443-1452 |
| URI: | http://hdl.handle.net/123456789/30708 |
| ISSN: | 0042-6075 |
| Appears in Collections: | IJC-B Vol.45B(06) [June 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(6) 1443-1452.pdf | 1.57 MB | Adobe PDF | View/Open |
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