NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.47 [2009] >
IJEB Vol.47(02) [February 2009] >

Title: Beneficial effects of modified egg* on oxidative stress in F₁- generation of metabolic syndrome-X induced Wistar rat
Authors: Taneja, Satish Kumar
Singh, Kshetrimatyum Birla
Keywords: Cu
Diabetes mellitus
Omega-3 fatty acids
Modified egg
Oxidative stress
Vitamin- E
Issue Date: Feb-2009
Publisher: CSIR
Abstract: Congenital malformations of neonates are one of the adverse effects of diabetic pregnancy which can be prevented by supplementation of vitamin E and C. The survived neonates usually are at higher risk to diabetes, hypertension, dyslipidemia and cardiovascular diseases that may possibly be prevented through antioxidants administration. In view of this information, the efficacy of modified poultry egg enriched with optimum minerals, vitamin E and omega-3 fatty acids was studied on F₁-generation, which were made to survive by feeding them this modified egg to diabetic mothers of Wistar rats. The survived F₁-generation displayed hyperglycemia, dyslipidemia and hypertension like their parents, evaluated after three months of the experiment. Their mineral status revealed a higher Zn and lower Cu, Mg and Mn levels in liver and kidney. Their lipid peroxidation products were however higher and the enzyme activities of superoxide dismutase, catalase, glutathione- S-transferase, glutathione reductase, glutathione (reduced) and glucose -6 phosphate dehydrogenase were significantly lower. In the other group of F₁-generation, fed modified egg mixed diet, a significant reduction in the blood pressure, serum glucose, serum lipid profile, and the lipid peroxidation products, and a significant increase in the activities of enzymes per se with reversal of Zn, Cu, Mg and Mn levels closer to the control group were recorded. The data suggest that the modified egg can ameliorate the oxidative stress in F₁- generation of diabetic rats by improving the mineral status in their body.
Page(s): 104-112
ISSN: 0019-5189
Source:IJEB Vol.47(02) [February 2009]

Files in This Item:

File Description SizeFormat
IJEB 47(2) 104-112.pdf120.19 kBAdobe PDFView/Open
 Current Page Visits: 67 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 167096 since 01-Sep-2015  Last updated on 28-Jun-2016Webmaster: