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Title: A facile one-pot synthetic route to substituted fused tetrahydropyrimidines. Part 41: Synthesis of 1-(aralkyl/aryl)-3- (alkyl/aralkyl/aryl)-5-oxo-l,2,3,4,5,6,7,8-octahydroquinazolines and 1-(aralkyl/aryl)-3- (alkyl/aralkyl/aryl)-7,7-dimethyl-5-oxo- 1,2,3,4,5,6,7,8-octahydroquinazolines
Authors: Chanda, Kaushik
Dutta, Milan C
Vishwakanna, Jai N
Keywords: Octahydroquinazolines;Cyclocondensation;Cyclic enaminones;Formaldehyde;Primary arriines
Issue Date: Apr-2006
Publisher: NISCAIR-CSIR, India
IPC Code: Int.C1.7 C 07 D
Abstract: A facile one pot pathway has been developed for the synthesis of novel 1-(aralkyl/aryl)-3-(alky/aralkyl/aryl)-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazolirles 2a-e and 1-(aralkyl/aryl)-3-(alkyl/aralkyl/ary1)-7,7-dimethy1-5-oxo-1,2.3,4,5,6,7.8- octahydroquinazolines 2f-k by the cyclocondensation of cyclic enaminones la-d with formaldehyde and primary amines in refluxing methanol in good yields.
Page(s): 1076-1079
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(04) [April 2006]

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