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Title: Pharmaceutical, physico-chemical and clinical study on "Shuddha Manahshila" with special reference to Kasa Roga
Authors: Kumar, Atul
Keywords: Ayurvedic drugs;Shuddha Manahshila;Standardization;Kasa roga;Cough;Bronchitis
Issue Date: Jul-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int Cl.7: A61K 33/36; A61K 33/04; A61K 35/78; A61K 35/12; A61P 11/00; A61P 11/14; A61P 11/08; A61P 11/06; A61P 29/00; A61P 37/08
Abstract: Manahshila (Realgar; Arsenic disulphide- As2S2), a bright red-orange coloured mineral, is a compound of arsenic and sulphur in 2:2 ratio, which has been described under Uprasa Varga in Rasa Shastra of Ayurveda. It is found in ore form in nature and can also be made artificially. Manahshila is one of the mineral drugs that has history of usage as old as Vedic period. In Rigveda, its usage has been mentioned for environmental purification; whereas, in Athrvaveda and Purana Granthas, its externo-internal usage is mentioned. Manahshila can therapeutically be used only after Shodhana (purification & detoxification). In the present study, the drug was prepared by processing (Bhavita) from approved are of Manahshila with Adraka Svarasa (ginger juice) for 7 days to make the drug more potent for Kasa Raga (cough/bronchitis). The physico-chemical parameters of the prepared drug were also established for the first time by comparing them with the crude drug, which was novel from pharmaceutical point of view. The clinical study of the drug was performed in 25 patients, at a dose of 10-25 mg, three times a day, for one month, with the adjuvant of Madhu (honey). The drug gave good results, particularly in Vataja Kasa (eosinophilia).
Page(s): 240-246
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.03(3) [July 2004]

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