Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/30539
Title: Yb(OTf)3-catalyzed Mannich reaction of imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyrimidines
Authors: Pericherla, Kasiviswanadharaju
Shelke, Ganesh M
Kothari, Yash Chandresh
Kumar, Anil
Keywords: Multicomponent reaction;Imidazo[1,2-a]pyridine;Pyrazolo[1,5-a]pyrimidine;Ytterbium triflate;One-pot synthesis
Issue Date: Feb-2015
Publisher: NISCAIR-CSIR, India
Abstract: An efficient one-pot condensation reaction of imidazo[1,2-a]pyridine/pyrazolo[1,5-a] pyrimidines, aldehydes and acetamide has been investigated using Yb(OTf)3 as catalyst in 1,4-dioxane. The reaction furnishes good to excellent yield of 1-amidomethyl-imidazo[1,2-a]pyridines and 1-amidomethyl-pyrazolo[1,5-a]pyrimidines along with small quantities of bis(imidazo[1,2-a]pyridyl)methanes and bis(pyrazolo[1,5-a]pyrimidinyl)methanes. The product distribution is found to be dependent on the nature of imidazo[1,2-a]pyridine/pyrazolo[1,5-a]pyrimidines and aldehydes.
Page(s): 290-300
URI: http://hdl.handle.net/123456789/30539
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections: IJC-B Vol.54B(02) [February 2015]

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