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http://nopr.niscair.res.in/handle/123456789/30531| Title: | Microwave-induced synthesis and anti-nemic activity of 4-amino-3- mercapto-5-pyridin-2-yl-4H-1,2,4-triazole Schiff bases |
| Authors: | Mandal, Abhishek Dutta, T K Gupta, R L |
| Keywords: | Schiff bases;Triazoles;Fusaric acid;Nematicide;Meloidogyne incognita;Rotylenchulus reniformis |
| Issue Date: | Feb-2015 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of twenty Schiff bases, 4-(benzylideneamino)-3-mercapto-5-pyridin-2-yl-4H-1,2,4-triazoles 6a-t, designed incorporating the picolinic acid moiety present in
fusaric acid, a natural nematicide isolated
from Fusarium oxysporum EF119, have been
synthesized in MW-induced conditions and characterized using 1H and 13C NMR, FT-IR spectroscopy and
elemental analysis. The Schiff bases obtained in high yields and screened
for anti-nemic activity against Meloidogyne
incognita and Rotylenchulus
reniformis. Some of the test
compounds show promising nematicidal
and nematode repelling activity. 4-(4-Methoxybenzylideneamino)-3-mercapto-5-pyridin-2-yl-4H-1,2,4-triazole 6m, exhibits the
highest nematicidal activity (LC50=218  g mL-1, M. incognita and 174 g mL-1, R. reniformis).
|
| Page(s): | 228-239 |
| URI: | http://hdl.handle.net/123456789/30531 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.54B(02) [February 2015] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 54B(2) 228-239.pdf | 229.81 kB | Adobe PDF | View/Open |
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