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|Title:||Clastogenic effects of synthetic food dyes using Salmonella typhimurium and Allium cepa test systems|
Katnoria, Jatinder Kaur
|Keywords:||Allium cepa;Chromosomal aberration;Heavy metals;Orange red;Salmonella typhimurium;Sky blue|
|Abstract:||The present study embodied the mutagenic/genotoxic potential of two most commonly used synthetic food dyes, viz., sky blue and orange red, employing Ames Salmonella histidine reversion point mutation assay and Allium cepa root chromosomal aberration assay. It was observed that sky blue and orange red dyes showed 6-fold increase in TA100 strain from the spontaneous count, whereas they showed non-mutagenic response in TA98 tester strain of S. typhimurium. In the chromosomal aberration assay, sky blue and orange red dyes induced 50.90 and 64.48% total aberrant cells, respectively.|
|ISSN:||0975-0967 (Online); 0972-5849 (Print)|
|Appears in Collections:||IJBT Vol.13(4) [October 2014]|
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