Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/29894
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHsu, Ching-Yun-
dc.contributor.authorYeh, Tsan-Huei-
dc.contributor.authorHuang, Meng-Yuan-
dc.contributor.authorHu, Shene-Pin-
dc.contributor.authorChao, Pi-Yu-
dc.contributor.authorYang, Chi-Ming-
dc.date.accessioned2014-11-12T11:09:20Z-
dc.date.available2014-11-12T11:09:20Z-
dc.date.issued2014-10-
dc.identifier.issn0975-0959 (Online); 0301-1208 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/29894-
dc.description388-395en_US
dc.description.abstractThe distribution of chlorophyll-related compounds (CRCs) derived from dietary spinach was investigated in different organs the rabbits. The rabbits in the experimental group consumed 100 g of freeze-dried spinach powder after a 24 h fasting period and sacrificed 2, 4, 8, 12 and 24 h later and in the control group sacrificed after the 24 h fasting period. The main CRCs in the liver were found to be chlorophyll (Chl a) and b, chlorophyllide (Chlide) a and b, pheophytin (Phe) a and b and pheophorbide (Pho) a and b, which reached their peak values at 8 h post-feeding. The gallbladder contained mainly Chlide a and a', Pho a and a', Pho b and b', which peaked their values at 2 h post-feeding. Pho a and b were consistently observed in the blood and peaked at 12 h post-feeding. The earlier appearance of Chlide a', Pho a' and Pho b' in the gallbladder compared to the liver indicated that these CRCs were compartmentalized differently and might undergo the same type of vectorialized transport as characterized for the bile salts. Pho levels peaked later in the blood compared to the liver, suggesting that Pho might be released into the peripheral blood circulation from the liver. In conclusion, Chlide and Pho were the principal Chl metabolites in the rabbits. Our data may expand our understanding of the metabolism and biodistribution of CRCs in the human body. A number of biological functions, including anti-oxidation, anti-tumor and anti-aging have recently been attributed to CRCs, it will be interesting to explore, if the binding of Chlide and Pho to other nutrients or trace metal ions in the body mediate their biological functions. en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJBB Vol.51(5) [October 2014]en_US
dc.subjectChlorophyll-related compoundsen_US
dc.subjectCatabolites of chlorophyllen_US
dc.subjectLiveren_US
dc.subjectGallbladderen_US
dc.subjectDistributionen_US
dc.titleOrgan-specific distribution of chlorophyll-related compounds from dietary spinach in rabbitsen_US
dc.typeArticleen_US
Appears in Collections:IJBB Vol.51(5) [October 2014]

Files in This Item:
File Description SizeFormat 
IJBB 51(5) 388-395.pdf154.17 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.