Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/29893
Title: In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells
Authors: Sharma, Vikas
Hussain, Shabir
Gupta, Moni
Saxena, Ajit Kumar
Keywords: Mentha Spp.;Cancer cells;SRB assay
Issue Date: Oct-2014
Publisher: NISCAIR-CSIR, India
Abstract: In vitro anticancer potential of methanolic and aqueous extracts of whole plants of Mentha arvensis, M. longifolia, M. spicata and M. viridis at concentration of 100 µg/ml was evaluated against eight human cancer cell lines — A-549, COLO-205, HCT-116, MCF-7, NCI-H322, PC-3, THP-1 and U-87MG from six different origins (breast, colon, glioblastoma, lung, leukemia and prostate) using sulphorhodamine blue (SRB) assay. Methanolic extracts of above-mentioned Mentha Spp. displayed anti-proliferative effect in the range of 70-97% against four human cancer cell lines, namely COLO-205, MCF-7, NCI-H322 and THP-1; however, aqueous extracts were found to be active against HCT-116 and PC-3. The results indicate that Mentha Spp. contain certain constituents with cytotoxic properties which may find use in developing anticancer agents.
Page(s): 416-419
URI: http://hdl.handle.net/123456789/29893
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.51(5) [October 2014]

Files in This Item:
File Description SizeFormat 
IJBB 51(5) 416-419.pdf39.34 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.