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Title: Phytochemical studies and antimicrobial activity of babool seeds
Authors: Srivastava, M
Kumar, G
Mohan, R
Malhotra, S
Keywords: Antibacterial;Babool;Bacterial strains;Extracts;Seed
Issue Date: Nov-2014
Publisher: NISCAIR-CSIR, India
Abstract: The antibacterial activity of seed extracts of A. nilotica, P. juliflora and L. leucocephala was determined in vitro using disc diffusion method against different bacterial strains viz. S. aureus, E. coli, P. aeruginosa, K. pneumonia and S. typhi. Dried powder was subjected to successive hot extraction method to obtain various extracts viz. n-hexane, chloroform, acetone, alcohol and water. Assay was performed at a dose of 100 mg/ml, compared to standard Amikacin (30 mg/ml). Maximum inhibition zone of 10 mm was observed by acetone, alcohol and water extract of A. nilotica against E. coli, S. typhi, S. aureus and P. aeruginosa respectively. P. juliflora extracts showed activity (8 mm) against S. aureus and S. typhi only. In L. leucocephala, n-hexane, alcohol and water extractive showed more prominent activity (8 mm). E. coli is neither inhibited by P. juliflora nor by L. does leucocephala extract. Hence a considerable zone of inhibition was observed by all the three babool species, among which A. nilotica exhibit most significant activity against tested strains followed by L. leucocephala and P. juliflora. The study prospects for detailed investigation on isolation and activity guided fractionation of babool seed extracts and their utilization as potential antimicrobials.
Page(s): 724-728
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.73(11) [November 2014]

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