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Title: A practical synthetic approach to a trans-cyclohexane-bearing C-glucoside as potent SGLT2 inhibitor
Authors: Zhang, Shuo
Yu, Xiu Ling
Wang, Wen Jin
Wang, Jian Wu
Zhao, Gui Long
Keywords: Cyclohexane;C-Glucoside;SGLT2 inhibitor
Issue Date: Sep-2014
Publisher: NISCAIR-CSIR, India
Abstract: An improved synthetic approach to a potent SGLT2 inhibitor, 1-deoxy-1-{4-methoxy-3-[(trans-4-n-propylcyclohexyl)methyl]-phenyl}-β-D-glucose 1 has been developed. This facile approach is highlighted by practicality, reproducibility and high yield. Several alternative routes are also investigated and discussed.
Page(s): 1205-1210
ISSN: 0975-0975(Online); 0376-4710(Print)
Appears in Collections:IJC-B Vol.53B(09) [September 2014]

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