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Title: Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one
Authors: Mulwad, V V
Hegde, A S
Keywords: Bromodeoxybenzoin
Antimicrobial activity
Issue Date: Jan-2009
Publisher: CSIR
Abstract: 3-Acetyl-4-hydroxy-2H[1]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA to give 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HCl in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2-elimination. All compounds have been screened for antimicrobial activity. They do not show significant activity.
Description: 128-133
ISSN: 0376-4699
Appears in Collections: IJC-B Vol.48B(01) [January 2009]

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