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Title: Review on biological importance of endoperoxides and their various routes of synthesis
Authors: Patel, Hitesh D
Christian, Dayena J
Keywords: Anti-bacterial;Anti-malarial;Anti-tumor;Artemisinine;Endoperoxide
Issue Date: Jul-2014
Publisher: NISCAIR-CSIR, India
Abstract: This review paper describes the synthesis of different endoperoxides, which exhibit anti-malarial, anti-cancer and other biological activity. This review is primarily based on artemisinine. Many researchers have proved that artemisinine is active in malaria and cancer. It is also proved that in artemisinine, the endoperoxide bond plays a key role in the fight against disease. It is expected that this review will provide first-hand information on endoperoxide chemistry to organic chemists, pharmacologists and medicinal chemists who are working on anti-malarial and anti-cancer drug development.
Page(s): 835-857
ISSN: 0975-0975(Online); 0376-4710(Print)
Appears in Collections:IJC-B Vol.53B(07) [July 2014]

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