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Title: Pharmacognostic evaluation of Tinospora cordifolia (Willd.) Miers and identification of biomarkers
Authors: Choudhary, Namrta
Siddiqui, MB
Khatoon, Sayyada
Keywords: Berberine;Microscopy;Pharmacognosy;Tinosporaside;Tinospora cordifolia
Issue Date: Jul-2014
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl.8: A61K 36/00, CO1, CO7
Abstract: Tinospora cordifolia (Willd.) Miers, (Guduchi) is an evergreen perennial climber belongs to the family Menispermaceae. It is a plant of significant medicinal importance in the indigenous systems of medicine and designated as Rasayana. All the parts of this plant are reported for various ethnobotanical and therapeutic uses. Vegetative aerial parts, viz. leaves, stem and aerial root were collected in various seasons and studied for macroscopical, anatomical, physicochemical and phytochemical studies. Microscopically leaf of T. cordifolia showed presence of anomocytic stomata, unicellular trichomes. Stem showed wheel shaped appearance at the transverse cut surface, a peculiar characteristic feature of the family Menispermaceae. Stem and aerial root exhibit abundant mucilage canals, dense ceratenchyma and characteristics wedge shaped medullary rays. Phytochemically, the various extracts showed the presence of diverse phytochemicals such as alkaloids, glycosides, polyphenols, steroids, tannins, etc. Leaf of T. cordifolia showed the maximum concentration of sugar, starch, flavonoids, phenolic, and tannin content as compare to aerial roots and stem. Tinosporaside and berberine were evaluated as biomarkers for the plant T. cordifolia using TLC fingerprinting.
Page(s): 543-550
ISSN: 0975-1068 (Online); 0972-5938 (Print)
Appears in Collections:IJTK Vol.13(3) [July 2014]

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