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Title: Kinetic modelling of coupled transport across biological membranes
Authors: Korla, Kalyani
Mitra, Chanchal K
Keywords: Antiport;Symport;Simulation;Octave;Michaelis-Menten kinetics
Issue Date: Apr-2014
Publisher: NISCAIR-CSIR, India
Abstract: In this report, we have modelled a secondary active co-transporter (symport and antiport), based on the classical kinetics model. Michaelis-Menten model of enzyme kinetics for a single substrate, single intermediate enzyme catalyzed reaction was proposed more than a hundred years ago. However, no single model for the kinetics of co-transport of molecules across a membrane is available in the literature. We have made several simplifying assumptions and have followed the basic Michaelis-Menten approach. The results have been simulated using GNU Octave. The results will be useful in general kinetic simulations and modelling.
Page(s): 93-99
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.51(2) [April 2014]

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