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Title: An investigatory study of antibacterial activity of functionalized spirooxindoles
Authors: Kidwai, Mazaahir
Jain, Arti
Singh, Satendra
Nemaysh, Vishal
Luthra, Pratibha Mehta
Keywords: Spirooxindoles;Target oriented synthesis;Green methodology;Multicomponent reaction;Pharmacological activity
Issue Date: Apr-2014
Publisher: NISCAIR-CSIR, India
Abstract: Synthesis of functionalized spirooxindoles have been reviewed and it has been proposed that the unique core ring system that is common to this family of compounds arises by a biological Knoevengal-Michael-Domino cyclization along with the attachment of hydrophobic alkyl chain linkage. These newly synthesized compounds have been also tested for their in vitro antibacterial activities against some bacterial strains viz. Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa.
Page(s): 399-411
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.53B(04) [April 2014]

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