NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(12) December 2008] >

Title: Tin(lV) catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions
Authors: Rameshwar, N
Parthasarathy, T
Reddy, A Ram
Keywords: Biginelli reaction
Tin(IV) chloride
Solvent-free condition
Issue Date: Dec-2008
Publisher: CSIR
Abstract: One pot condensation of ethyl acetoacetate or methyl acetoacetate with various para and ortho substituted aromatic aldehydes and urea or thiourea by tin(IV) chloride affords twenty-one different substituted 3,4–dihydropyrimidin-2-(1H)-ones. Tin(IV) chloride has emerged as a powerful catalyst for the preparation of 3,4–dihydropyrimidin-2-(1H)-ones under simple and mild conditions. It is compatible with a wide variety of substituents in the aromatic aldehyde. Substituents at para position in aldehyde are more effective than the substituents at ortho position. Both the β–ketoesters, and urea or thiourea are equally effective towards an efficient 3,4–dihydropyrimidin-2-(1H)-one synthesis.
Page(s): 1871-1875
ISSN: 0376-4699
Source:IJC-B Vol.47B(12) December 2008]

Files in This Item:

File Description SizeFormat
IJCB 47B(12) 1871-1875.pdf133.76 kBAdobe PDFView/Open
 Current Page Visits: 846 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 171455 since 01-Sep-2015  Last updated on 30-Jun-2016Webmaster: