Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/26524
Title: Synthesis of Some New 1-[5'-{(2-benzothiazolylthio)methyl}-1', 3', 4'-thiadiazol-2'-yl]-4-substituted-3-chloro-2-azetidinones : Antimicrobial Agent
Authors: Guru, Niharika
Srivastava, S D
Issue Date: Jul-2001
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2-arylideneamino-5-[(2-benzothiazolylthio) methyl]-1', 3', 4'-thiadiazoles (4a-j) have been synthesized via condensation of 2-amino-5-[(benzothiazolylthio)methyl]-1, 3, 4, thiadizole 3 with various carbonyl compounds. Cycloaddition of chloroacetylchloride to 4 gives 1-[5'-{(2-benzothiazolylthio) methyl}-1', 3', 4'-thiadiazol-2'-yl] -4-substituted -3-chloro-2-azetidinones (5a-j) have been synthesized as the final products. All the products have been screened for their antifungal and antibacterial activity against some selected pathogens and found to exhibit mild to pronounce activity.
Page(s): 601-605
URI: http://hdl.handle.net/123456789/26524
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.60(07) [July 2001]

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