Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/26506
Title: Synthesis of some novel class of isoxazoline and isoxazolidine derivatives in ionic liquid via 1,3-dipolar cycloaddition reaction of dihydropyran derived nitrones and their antimicrobial activities
Authors: Chakraborty, Bhaskar
Samanta, Amalesh
Sharma, Chiran Devi
Khatun, Nasima
Keywords: Dihydropyran derived nitrones;Cycloaddition reaction;Novel isoxazolidine & isoxazolines;Ionic liquid;Peptides;Aldehyde synthesis;Antimicrobial activity
Issue Date: Feb-2014
Publisher: NISCAIR-CSIR, India
Abstract: 1,3-Dipolar cycloaddition of dihydropyran derived nitrones synthesized from 2,3 dihydro 4H-pyran and various hydroxylamines, with electron deficient alkynes are found to have significant rate acceleration and improved yields of isoxazolines in 1-Butyl-3-methylimidazolium based ionic liquids while with enals exclusively endo isoxazolidines are obtained with high selectivity. Synthetic potentiality of the novel isoxazolines and nitrones have been also tested successfully in peptide and aldehyde synthesis. All the novel isoxazoline and isoxazolidine derivatives have been screened for antimicrobial activities and found to be active.
Page(s): 218-226
URI: http://hdl.handle.net/123456789/26506
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.53B(02) [February 2014]

Files in This Item:
File Description SizeFormat 
IJCB 53B(2) 218-226.pdf95.78 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.