Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/26480
Title: Synthesis and Antimicrobial Activity of Some New N-Methylpiperazinylthiadiazoles and Their Azetidinones
Authors: Jaish, L
Srivastava, S K
Issue Date: Apr-2001
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2-arylidenimino-5-( N4-methyl-Nl-piperazinylmethyl)-1 ,3,4-thiadiazole, 4, have been synthesized via condensation of 2-amino -5-(N4-methyl-N1-piperazinylmethyl)-1,3,4-thiadiazole with various carbonyl compounds. Cycloaddition of chloroacetyl chlorride to 4 gives 1-[5'-(N4- methyl-N1-piperazinylmethyl)-1', 3', 4'-thiadiazole-2'-yl]-4-substituted-3-chloro-2-azetidinones, 5. Compounds 4 and 5 have been screened for their antibacterial and antifungal activities.
Page(s): 331-335
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.60(04) [April 2001]

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