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IJC-B Vol.47B(11) [November 2008] >


Title: Conventional and microwave induced synthesis of various azetidinone and thiazolidinone derivatives from 3-[(1E)-1-aza-2-(2-chloro-7-methoxy-3-quinolyl)-vinyl]-4-(aryldiazenyl) phenol and their antimicrobial screening
Authors: Patel, Jigisha A
Mistry, B D
Desai, K R
Keywords: Azetidinone
Thiazolidinone
Antibacterial
Antifungal
Antitubercular activity
Issue Date: Nov-2008
Publisher: CSIR
Abstract: 3-Chloro-4-(2-chloro-7-methoxy-3-quinolyl)-1-[3-hydroxy-6-(aryldiazenyl) phenyl] azetidin-2-one 2 and 2-(2-chloro-7-methoxy-3-quinolyl)-3-[3-hydroxy-6-(aryldiazenyl) phenyl]-1, 3-thiazolidin-4-one 3 have been synthesized by the reaction of 3-[(1E)-1-aza-2-(2-chloro-7-methoxy-3-quinolyl)-vinyl]-4-(aryldiazenyl) phenol 1 with chloroacetylchloride and mercapto acetic acid, respectively. Both the reactions have been carried out by conventional and microwave methods. These compounds have been screened for their antibacterial, antifungal and antitubercular activity against different microorganisms.
Page(s): 1695-1700
ISSN: 0376-4699
Source:IJC-B Vol.47B(11) [November 2008]

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