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Title: Iodine promoted simple synthesis of benzimidazole acyclonucleosides
Authors: Yadav, Tej Bahadur
Singh, Virendra
Keywords: Benzimidazole;Nucleosides;o-phenylenediamine;Iodine;Acetic acid;Aldoses
Issue Date: Dec-2013
Publisher: NISCAIR-CSIR, India
Abstract: A novel one-pot ecofriendly synthesis of 2,5,6-trisubstituted-1H-benzimidazole nucleoside derivatives have been accomplished stepwise. i.e. substituted o-phenylenediamine and aldoses using iodine as an oxidant or promoter in acetic solution at room temperature. A practical method has been developed for conversion of unprotected and unmodified aldoses to aldo-benzimidazoles.
Page(s): 1536-1539
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.52B(12) December 2013]

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