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Title: Recombinant mycobacterial proteins Future directions to improve protective efficacy
Authors: Sharma, Anil K
Khuller, G K
Issue Date: Dec-2001
Publisher: NISCAIR-CSIR, India
Abstract: A large number of subunit vaccine candidates have recently been developed as alternatives to Mycobacterium bovis Bacillus Calmette-Guerin (BCG), which gives unpredictable and highly variable protection against tuberculosis. Immunological potential of various recombinant proteins against mycobacterial infections has been discussed. Further, strategies have been suggested, which include development of constructs coexpressing cytokines or regimens utilizing recombinant proteins for further improving the protective efficacy.
Page(s): 1214-1219
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.39(12) [December 2001]

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