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Title: Hepatoprotective effect of Bhumyamalki (Phyllanthus fraternus Webster) and Phaltrikadi decoction in patients of acute viral hepatitis
Authors: Singh, Harbans
Keywords: Viral hepatitis
Hepatoprotective activity
Issue Date: Oct-2008
Publisher: CSIR
IPC CodeInt. Cl. ⁸ : A61K36/00, A61P1/04, A61P1/06, A61P1/14, A61P1/16
Abstract: Hepatitis infection has become a major worldwide health problem because the potential nature of course of the disease to cirrhosis and the hepatocellular carcinoma (HCC). Acute viral infection is the most common cause of all forms of hepatitis. The viral hepatitis have been thought to be self limiting in nature but sometimes majority of patients of viral hepatitis have been observed ending up with a serious complications like hepatic failure, etc. So, the clinical study was planned to evaluate the hepatoprotective effect of Bhyumyamalki (Phyllanthus fraternus Webster) and Phaltrikadi decoction (an Ayurvedic herbal composition) on scientific parameters. In the clinical trial, three groups of patients of viral hepatitis have been studied to evaluate the hepatoprotective effect of Bhumyamalki and Phaltrikadi decoction. The first group was given 50 ml of freshly prepared Bhumyamalki decoction, made from 10 gm of crude drug, twice daily. The second group was given a standardized decoction of herbal composition Phaltrikadi decoction, in a dosage of 50 ml made from 10 gm of crude drug, twice daily. The third group was given 100 gm of glucose powder daily. The trial was conducted for one month and liver functions test were periodically evaluated to assess the hepatoprotective effect of drugs under trial. At the end of the trial, group first and second exhibited hepatoprotective efficiency over the control.
Page(s): 560-565
ISSN: 0972-5938
Source:IJTK Vol.07(4) [October 2008]

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