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Title: Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats
Authors: Ghosh, Sumana
Suryawanshi, S A
Issue Date: Aug-2001
Publisher: NISCAIR-CSIR, India
Abstract: Administration of aqueous extracts of V. rosea nower and leaf have been found to regulate the blood sugar level in all oxan diabetic male albino rats. V. rosea therapy not only produced blood glucose homeostasis but also reversed changes in carbohydrate, protein, lipid metabolisms and metabolic and pnthologic chnnges that took place in pancreatic islet cells, liver and kidney following a single dose (150 mg/kg body weight) of al loxan monohydrate. B-cell secretory activity resumed near-normalcy as evidenced by near-normal serum insulin concentration and electron-microscopic study proving that V. rosea manifests its beneficial activity through B-cell rejuvenation, regeneration and stimulation.
Page(s): 748-759
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.39(08) [August 2001]

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